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Hormones and Health Risks (Part I) (revised)
In This Issue
Hormones & Heart Risk
Declining Testosterone A Major Risk Factor
DHEA - Preventive Effect
Estrogen & Aggressive Prostate Cancer
High and Low Estradiol Levels Linked to Mortality
Testosterone Unrelated to Prostate Cancer
Low Testosterone & Atrial Fibrillation
Sexual Functioning can be Restored
Low Testosterone & Risk of Death
Erectile dysfunction & CVD
Androgen replacement therapy
Legislation & Legal Issues
Website & Personal News
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Feb. 7, 2009
As we age our hormone levels tend to become altered from their normal levels. In men, some hormones like DHEA and Testosterone drop, while others like the estrogens tend to increase.
While the exact levels are not always of critical importance, the balance between them is.
In the first part of this two part newsletter, I've selected some articles that address the importance of maintaining a man's hormone levels in balance.  In part 2, (coming next) I will address similar  issues for women.
Testing hormone levels and keeping your hormones in balance, (not necessarily at specific levels) is critcally important to good health and well being. 
Sex Hormones Link to Heart Risk!
Men are more prone to - and likely to die of - heart disease compared with women of a similar age - and sex hormones are to blame, according to a new University of Leicester led study.
Are Declining Testosterone Levels A Major Risk Factor for Ill-Health in Aging Men?
As men grow older, testosterone levels fall, with a steeper decline in unbound or free testosterone compared with total testosterone concentrations. Lower testosterone levels have been associated with poorer cognitive function, and with impaired general and sexual health in aging men.
New evidence suggests preventive effect of herbal supplement in prostate cancer 
DHEA is a natural circulating hormone and the body's production of it decreases with age.  Men take DHEA as an over-the-counter supplement because it has been suggested that DHEA can reverse aging or have anabolic effects since it can be metabolized in the body to androgens.
Estrogen drives distinct, aggressive prostate cancer
Using a breakthrough technology, researchers led by a Weill Cornell Medical College scientist have pinpointed the hormone estrogen as a key player in about half of all prostate cancers.
Both High and Low Estradiol Levels Linked to Mortality in Men With Chronic Systolic Heart Failure.
Both low and high serum levels of estradiol, compared with mid-range levels, are significantly and independently associated with increased all-cause mortality in men with chronic systolic heart failure, suggests a prospective observational study in the May 13, 2009 issue of the Journal of the American Medical Association
Testosterone seen unrelated to prostate cancer risk
Natural levels of a man's testosterone do not affect his prostate cancer risk as some had thought, a finding that should spur scientists to rethink their approach to the disease, researchers said.
Low Testosterone Levels Associated With Lone Atrial Fibrillation in Men
Reduced testosterone levels in men may increase the risk of lone atrial fibrillation (AF), according to a report in the January issue of Clinical Cardiology. 
Sexual Functioning in Men can be Fully Restored Naturally
Men who have taken the time to get their hormone levels in balance never have to consider popping a Viagra. Even men who still produce plenty of testosterone can find themselves in need of hormone balancing when things start to go wrong in the bedroom. This is because processes are at work preventing testosterone from doing the work it was meant to do.
Low Testosterone in Men Linked to Huge Increase in Risk of Death
As reported in the Archieves of Internal Medicine, researchers at the VA Puget Sound Health Care System and the University of Washington at Seattle, evaluated whether low testosterone levels are a risk factor for mortality in male veterans. Men in the low testosterone group had an 88 percent increased risk of death compared to the group who had normal testosterone levels.
Erectile dysfunction can be strongly related to the development of CVD
This first study of its kind tested whether erectile dysfunction (ED) can be used to reclassify patients according to their future risk of developing cardiovascular disease (CVD) beyond traditional risk factors.  Results of the 12-year research study are published in the January 26, 2010 issue of the Journal of the American College of Cardiology and show that ED may be a warning sign of a future cardiovascular event like heart attack, stroke, atherosclerosis, coronary artery bypass graft surgery, and congestive heart failure.
Androgen replacement therapy may ward off heart damage
A man's male hormones may ward off heart damage by helping vessels around the heart regenerate, suggest Australian researchers in a report posted January 13 in the Journal of Experimental Medicine. 

Legislation and Legal Issues

As mentioned in previous newsletters, the FDA was sucessfully sued by a Virgina-based attorney, Jonathan Emord, in four suits dating back to 1999 regarding its censorship of scientific data of natural substances. The Alliance for Natural Health USA (ANH-USA) and others accuse the FDA of ignoring four prior court orders and thereby breaching constitutional First Amendment freedom of speech tenets. They accuse the FDA of stubbornly refusing to respect the will of the courts. The FDA has about 3 weeks left to answer these claims.  
Senator John McCain has filed a new bill that can restrict your access to supplements and repeals key sections of the Dietary Supplement Health and Education Act. (DSHEA).  While I do believe Senator McCain means well in this endeavor, I don't think he has been well advised of the potential his bill has for creating havoc and restricting access to dietary supplements.   

WebSite and Personal News 

As I mentioned in my last newsletter, my new website,
is operational and its entry page is now the home page for both websites.  Thus, you will be able to seamlessly move from men's to women's issues and back. Some of the pages, like the newsletter archive and the products section are shared between both sites.
Ladies take note that I am currently working hard on the "Female Issues" section of the website, and hope to have it up and running within the next few weeks.
Our new search facility is working nicely and searches every page on both sites automatically, so if the information you need is on the site a link to it will appear on your search results page.  New information is available as soon as I put it on the site, and there are no pop-up advertisements. 
To implement a search, simply click the "Site Search" button located at the top left of every main page. You will then see a search screen where you can enter a keyword (or keywords) to search the site for.  Direct links to pages found allow you to quickly view information on many topics.
Our  newsletter archive contains copies of all previous newsletters. A link to the archive is on every main page of the website just below the newsletter sign-up box and also in the "page links" section of each newsletter issue.  
As always, if you enjoy this newsletter (or hate it), feel free to contact me with your comments.  And, if you really like it, please forward it to a friend using the "Forward email" link below. 
Jim Occhiogrosso
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Hormones and Health Risks (Part I)